Effects of subthalamic nucleus deep brain stimulation on sweating function in Parkinson’s disease
Published: March 2010
19 patients with idiopathic Parkinson’s disease (PD) were examined immediately before and 6 months after subthalamic nucleus deep brain stimulation (STN-DBS). Each examination session included registration of autonomic symptoms by means of a semi-structural questionnaire and recording of sympathetic skin response (SSR) from both palms and one sole. The neurophysiological measurements were compared to those of 19 sex-and age-matched healthy controls.
The number of patients with at least one abnormal SSR was reduced from 6 before the operation to 3 after the operation. These results, although based on a small sample, suggest that STN-DBS, in addition to its positive effect on mobility, might also favourably regulate sweat in idiopathic PD.
To view abstract click here
